461 - Christmas disease is hemophilia B - deficiency in factor IX.
462 - de Quervain’s disease is a stenosing tenosynovitis of the thumb extensors and abductors; pain elicited with Finkelstein’s test.
463 - Munchausen’s syndrome is factitious disorder - eponym given by Asher in 1951 after Baron Karl Munchausen (1720-1797) - retired German cavalry officer with a reputation for preposterous stories about his activities as a soldier - hunter.
464 - MacCallum’s plaques is irregular thickenings - usually in the left atrium - from subendocardial lesions - usually exacerbated by regurgitant jets.
465 -POEMS syndrome is polyneuropathy - organomegaly - endocrinopahty - M protein - and skin changes which may be seen in plasma cell dyscrasias; also known as Crow-Fukase syndrome in Japan.
466 - Santorini’s fissures is fissures in anterior aspect of cartilaginous portion of ear canal through which neurovascular tissues pass; may allow spread of ear disease to parotid joint - TMJ - soft tissues of upper neck.
467 - Glauber’s salt is sodium sulfate - laxative.
It consists of a pleura based shallow wedge-shaped consolidation in the lung periphery with the base against the pleural surface. It is named after Aubrey Otis Hampton.
469 - In chest radiography, the Westermark Sign, is a sign that represents a focus of oligemia (vasoconstriction) seen distal to a pulmonary embolus (PE). While the chest x-ray is abnormal in the majority of PE cases, the Westermark sign is seen in only 2% of patients.
The sign results from a combination of:
1. the dilation of the pulmonary arteries proximal to the embolus and
2. the collapse of the distal vasculature creating the appearance of a sharp cut off on chest radiography.
470 - Wickham’s striae is in lichen planus - papules are highlighted by a shiny surface with a lacy white pattern.