Wednesday, March 5, 2008

eponyms in medicine - part 31


301 - Degos disease is malignant atrophic papulosis; multisystem lymphocytic vasculitis characterized by thrombosis primarily of cutaneous small vessels as well as small vassels in GI tract - ocular - and CNS; has characteristic porcelain white atrophic lesion.

302 - Clara cells is cells found in the epithelium of terminal and respiratory bronchioles - devoid of cilia - present secretory granules in their apex and are known to secrete glycosoaminoglycans that probably protect the bronchiolar lining.

303 - Kikuchi’s disease is histiocytic necrotizing lymphadenitis - characterized by cervical lymphadenopathy with tenderness - fever - and night sweats; tends to occur in young women; histology can be confused with lymphoma.

304 - Retzius - veins of is numerous small veins in the retroperitoneum that connect the retroperitoneal viscera to the posterior abdominal wall; dilated in portal hypertension.

305 - Mounier-Kuhn syndrome is tracheomegaly - tracheobronchomegaly associated with recurrent pneumonia - copious purulent sputum production - hoarseness - load cough; presents in 30s-40s - more common in males; tracheal lumen increases with Valsalva; autosomal recessive.

306 - Marie-Strümpell disease is refers to ankylosing spondylitis in Europe.

307 - McMurray test is for diagnosing meniscal tear - passively flex hip and knee until heel touches buttock - steady the knee with one hand - externally rotate foot - then extend the knee to 90 degrees - return ot the beginning and then internally rotate the foot - then passively extend the knee to 90 degrees - feeling for clicks - PPV 83% for tears.

308 - Bateman’s senile purpura is purpura following trauma to severely sun-damaged skin of the dorsal forearm of elderly persons; months may be required for resolution of pigmentation from hemorrhage.

309 - RSH syndrome is Smith-Lemli-Opitz syndrome.

310 - Burow’s solution is aluminum acetate in water - invented in mid-1800s by ophthalmologist Karl Burow (a.k.a. by its tradename Domeboro).

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