Wednesday, March 5, 2008

eponyms in medicine - part 36

351 - Maffucci’s syndrome is enchondromatosis associated with soft tissue hemangiomas; associated with ovarian carcinomas and brain gliomas; essentially Ollier’s disease with hemangiomas.

352 - Heyde’s syndrome is association between bleeding from gastrointestinal angiodysplasia and severe aortic stenosis which may resolve with aortic valve replacement; may be explained by acquired type IIA von Willebrand’s syndrome; first described by Hyde in N Engl J Med 1958;259:196.

353 - Hansel’s stain is special stain used to detect eosinophiluria on the urine sediment.

354 - Conn’s syndrome is primary hyperaldosteronism - caused by an aldosterone-secreting tumor - resulting in hypertension - hypokalemia - hypernatremia - metabolic alkalosis - and low plasma renin.

355 - Kienböck disease is osteonecrosis of the carpal lunate that most commonly affects men between ages 20-40; sometimes history of trauma; may lead to end-stage arthritis of wrist with progression.

356 - Pancoast’s tumor is apical lung cancers in the superior pulmonary sulcus which invade neural structures around the trachea - including the cervical sympathetic plexus - leading to severe pain in distribution of the ulnar nerve and Horner’s syndrome on same side of the lesion.

357 - Ewing’s sarcoma is onion skinning; small round cell tumor of bone - 85% of cases there is a t(11;22)(q24:q12) translocation.

358 - Schafer’s maneuver is extensor plantar response by squeezing Achilles tendon suggesting upper motor neuron defect.

359 - Bernheim effect - reverse is in pulmonary embolism - right ventricular failure causing septum to bulge into and compromise left ventricular filling.

360 - Poiseuille’s law is flow proportional to fourth power of radius - inversely proportional to length.

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