Wednesday, March 5, 2008

eponyms in medicine - part 32


311 - Kupffer cells is phagocytic cells of the mononuclear phagocyte series found on the luminal surface of endothelial cells in hepatic sinusoids; they metabolize old RBCs - digest hemoglobin.

312 - Boston sign is in thyrotoxicosis - jerking of the lagging lid.

313 - Oppenheim’s sign is involuntary dorsiflexion of the toes when stroking the medial/anterior tibial surface superiorly to inferiorly - indicating upper motor neuron defect.

314 - Ross’s syndrome is tonic pupils (generally bilateral) - anhydrosis - and areflexia which may appear in a different pattern distribution; possible link with Holmes-Adie syndrome.

315 - Buerger’s sign is in peripheral vascular disease - red foot becomes pale with elevation.

316 - Hutchinson’s teeth is smaller and more widely spaced than normal and are notched on their biting surfaces; sign of congenital syphilis.the diagnostic criteria of the congenital syphilis are called the hutchinsons triad and they are

a- HUTCHINSONS TEETH

b- INTERSTITIAL KERATITIS

c- EIGTH NERVE DEAFNESS ( VESTIBULO COCHLEAR NERVE ).

if u wanna see how the hutchinson's teeth look like click here .


317 - job's syndrome - RECURRENT STAPHYLOCOCCAL CUTANEOUS INFECTIONS ARE MORE COMMON AMONG INDIVIDUALS WHO HAVE EOSINOPHILIA AND ELEVATED SERUM LEVELS OF IMMUNOGLOBULIN E. THIS IS CALLED JOB'S SYNDROME.

318 - Holmes-Adie syndrome is frequently affects young women - large - often irregular pupils - unilateral at onset as well as segmental palsy and segmental spontaneous movement of the iris - delayed constriction in response to near vision - delayed redilation after near vision - impaired accommodation - absent light reflex - and absent deep tendon reflexes; may be caused by degeneration of ciliary ganglion - followed by aberrant reinnervation of the pupilloconstrictor muscles.

319 - Felty’s syndrome is rheumatoid arthritis - splenomegaly - and neutropenia - and leg ulcers; associated with HLA-DR.

320 - RomaƱa’s sign is in the first week of Chagas disease - unilateral periorbital edema and swelling of the eyelid associated with reduviid bug of eye.

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