Thursday, February 21, 2008

eponyms in medicine - part 24

231 - hangman’s fracture is fracture of pars interarticularis of C2 - hyperextension injury.

232 - Castellani’s paint is topical fungicidal and bactericidal mixture of resorcinol (8 g) - acetone (4 mL) - magenta (0.4 g) - phenol (4 g) - boric acid (0.8 g) - industrial methylated spirit 90% (8.5 mL) - and water (to 100 mL); particularly effective against intertriginous tinea and acute Candida paronychia; named after Sir Aldo Castellani.

233 - McDonald’s sign is uterine corpus and cervix can be easily flexed on each other due to Hegar’s sign.

234 - Paget’s disease of vulva is intraepithelial adenocarcinoma - less than 1% of all vulva malignancies.

235 - Finkelstein’s test is in de Quervain’s tenosynovitis - dorsal thumb pain when the wrist is deviated in an ulnar fashion and the thumb is flexed across the palm.

236 - Rotor’s syndrome is poorly defined defects in hepatic uptake and storage of bilirubin; resembles Dubin-Johnson syndrome - but liver pigment missing.

237 - Duffy blood group system is named after Mr. Duffy - a patient with hemophilia in whom anti-Fya was discovered by Cutbush in 1950; abbreviation Fy used because “Du” had already been taken; Fy6 antigen is the receptor for Plasmodium vivax.

238 - Dubin-Johnson syndrome is mostly conjugated hyperbilirubinemia from defect in transport of bilirubin and other organic anions across the canaliculus; other liver function tests normal; accumulation of dark pigment in liver lysosomes.

239 - Vincent’s infection is acute necrotizing ulcerative gingivitis - occurring in patients with decreased resistance to infection - from concurrent infection with the symbiotic bacteria Fusobacterium fusiforme and Borrelia vincentii.

240 - Dance’s sign is empty right lower quadrant in children with ileocecal intussusception.

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