131 - Prehn's sign is elevation of painful testicle decreases pain of epididymitis.
132 - Ramirez sign is in deep vein thrombosis - sphygmomanometer cuff placed above knee inflated to 40 mm Hg causing pain at site of thrombosis.
133 - second disease is scarlet fever - aka scarlatina - caused by Strep pyogenes exotoxin - first described in 1626.
134 - Burkitt lymphoma is tumor manifesting at extranodal sites; associated with translocation of c-myc gene on chr 8 with IgH locus (chr 14) - kappa (chr 2) - or lambda light-chain (chr 22) locus; associated with EBV infection in African variety.
135 - Gordon’s maneuver is extensor plant response by squeezing the calf muscle suggesting upper motor neuron defect.
136 - Jones’s fracture is fracture at the base of the fifth metatarsal diaphysis.
137 - Hughes-Stovin syndrome is multiple pulmonary artery aneurysms with peripheral venous thrombosis.
138 - Siegrist streaks is linear hyperpigmented areas over choroidal vessels in hypertensive retinopathy.
139 - Blomstrand dysplasia is rare lethal disorder characterized by an increase in bone density and advanced skeletal maturationfrom inactivating mutation in PTHR-1 gene (also Jansen metaphyseal chondrodysplasia where there is an activating mutation).
140 - MELAS is mitochondrial encephalopathy with acidosis and stroke - onset in childhood - stroke-like episodes with hemiparesis - hemianopia - or cortical blindness; full expression of the disease leads to death often before age 20; 80-90% have point mutation in leucine tRNA in mtDNA.