eponyms in medicine - part 46

451 - Rothmann-Makai syndrome is a variant of idiopathic lobular panniculitis seen in infants - tends to be localized and spontaneously resolves; associated with autoimmune diseases such as juvenile rheumatoid arthritis - diabetes - and Hashimoto’s thyroiditis.

452 - Lugol’s solution is 5% iodine and 10% KI - a dose of 6.3 mg of I per drop - for giving iodine.

453 - Stoppa repair is hernia repair using tension-free intraparietal prosthetic mesh.

454 - Auenbrugger’s sign is epigastric bulge due to a massive pericardial effusion.

455 - Zahn - lines of is thrombi formed within a cardiac chamber or the aorta - may have apparent laminations - produced by alternating layers of paler platelets admixed with some fibrin - separated by darker layers containing more red cells.

456 - Cagot ear is absence of ear lobe; assocated with region in Pyrennes.

457 - Ham’s test is for diagnosing paroxysmal nocturnal hemoglobinuria - uses increased sensitivity of PNH-affected RBCs to lysis by complement; introduced in late 1930s.

458 - Forscheimer spots is in rubella - punctate soft palate macules.

459 - Apley grind test is for meniscal tears - flex patient’s leg to 90 degrees - then grind the tibial condyles against the femoral condyles with rotation motion in the varus and then valgus positions.

460 - clay shoveler’s fracture is fracture of spinous process of C7.

eponyms in medicine - part 26

251 - Duncan’s disease is X-linked lymphoproliferative syndrome - normal response to childhood infections but develop fatal lymphoproliferative disorders after infection with EBV; most patients with this syndrome die of infectious mononucleosis.

252 - Gerstmann syndrome is finger agnosia - agraphia - right-left disorientation - and dyscalculia.

253 - Jamaican vomiting sickness is poisoning from hypoglycin A in unripe ackee fruit; hypoglycin A is potent hypoglycemic agent that decreases rate of fatty-acid beta oxidation probably by inhibition of acyl dehydrogenase flavin-dependent oxidation; causes liver damage indistinguishable from Reye’s syndrome.

254 - Adie syndrome, sometimes known as Holmes-Adie's syndrome or Adie's Tonic Pupil, is a neurological disorder which affects the pupil of the eye and the autonomic nervous system.[1] It is caused by damage to the postganglionic fibers of the parasympathetic innervation of the eye, usually by a viral or bacterial infection which causes inflammation, and characterized by a tonically dilated pupil.Adie syndrome presents with three hallmark symptoms, namely abnormal pupil size, loss of deep tendon reflexes and diaphoresis.[1] Other signs may include hyperopia due to accommodative paresis, photophobia and difficulty reading.

255 - clay shoveler’s fracture is fracture of spinous process of C7.

256 - jacksonian march is in simple partial seizures - clonic movements of a single muscle group spreading to involve contiguous regions of the motor cortex.

257 - Goldenhar syndrome is syndrome of oculoauriculovertebral dysplasia characterized by unilateral deformity of the external ear and small ipsilateral half of the face with epibulbar lipodermoid and vertebral anomalies; autosomal dominant.

258 - Schwartz’s dictum is no acid - no ulcer.

259 - Young’s syndrome is clinical features similar to cystic fibrosis - including bronchiectasis - sinusitis - and obstructive azoospermia - but don’t have increased sweat chloride values - nor pancreatic insufficiency - nor abnormal nasal potential differences - nor the CF delta F508 mutation; affected individuals are often middle-aged males identified during evaluation for infertility.

260 - Mayer-Rokitansky-Küster-Hauser syndrome is absence of vagina from abnormality of müllerian development.